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A Faster Way to Diagnose Multiple Sclerosis: The Central Vein Sign in Routine Clinical Practice.

PubMed / Neurol Clin Pract · 2026-08-03 · By Gilmartin CGS, Paskin T, Clarke MA, et al. · Neurology. Clinical practice

A study published in Neurology: Clinical Practice examines the central vein sign (CVS) as a practical diagnostic tool for multiple sclerosis in routine clinical settings. The CVS, an MRI-based marker reflecting the perivenous distribution of MS lesions, may help clinicians reach an MS diagnosis more quickly and with greater accuracy. Faster, more reliable diagnosis has downstream implications for physical therapists managing patients with MS, as earlier confirmation can prompt timely referral and rehabilitation planning.

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