Exercise attenuates neuropathic pain and neuroinflammation in an obese rat model exhibiting diabetes-related metabolic dysfunction and features of type 2 diabetes.

A rat study found that exercise reduced neuropathic pain and neuroinflammation in obese animals with type 2 diabetes-related metabolic dysfunction. The findings suggest that physical activity may help counteract the pain sensitization and inflammatory processes associated with diabetic neuropathy. These results support the potential therapeutic role of exercise-based interventions for managing neuropathic pain in patients with obesity and type 2 diabetes.

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