(Cost-)effectiveness of a combined lifestyle intervention integrated into standard care for low back pain compared to usual care for people with persistent non-specific low back pain who are overweight or obese: Protocol for a randomised controlled trial with parallel economic and process evaluations (Back2Health).

This protocol describes the Back2Health randomised controlled trial, which will evaluate whether a combined lifestyle intervention integrated into standard care outperforms usual care for overweight or obese patients with persistent non-specific low back pain. Alongside the primary effectiveness analysis, the trial incorporates parallel economic and process evaluations to assess cost-effectiveness and implementation factors. Findings could inform how weight-related lifestyle interventions are embedded within routine low back pain management in physical therapy and broader healthcare settings.

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